Quantifying relative within-host replication fitness in influenza virus competition experiments
نویسندگان
چکیده
منابع مشابه
Quantifying relative within-host replication fitness in influenza virus competition experiments.
Through accumulation of genetic mutations in the neuraminidase gene, the influenza virus can become resistant to antiviral drugs such as oseltamivir. Quantifying the fitness of emergent drug-resistant influenza viruses, relative to contemporary circulating viruses, provides valuable information to complement existing efforts in the surveillance of drug-resistance. We have previously developed a...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2015
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2015.07.003